Avail our high-quality structural biology services to support your structure-based drug discovery from gene to protein co-crystal structures at prices starting as low as $14/hour
Are you looking for a highly-experienced structural biology team to support your structure-based drug discovery right from gene to protein co-crystal structures of small molecule compounds using x-ray crystallography at high resolution? Are you looking for a structural biology team to provide protein expression and protein purification services? If so, you have come to the right place.
Flatworld Solutions is a leading structural biology service provider and provides high-quality structural biology solutions to a global clientele. We provide a full package of services, right from construct design, custom protein production, protein characterization, and gene cloning and expression to x-ray diffraction data collection, crystal hit screening and optimization, and structure solving. We also offer cells expressing target proteins and recombinant proteins for functional assays.
Our Structural Biology Services
We are a leading structural biology research consultant as well as a structural biology services company and provide a wide range of services that help you accelerate your small-molecule drug discovery process. We have 16 years of experience in providing structural biology services to a global clientele.
Our structural biology services include -
X-ray Structural Studies Services
The team at Outsource2india has time and again demonstrated its strength in protein engineering to cater to the needs of crystallization. We have also designed multiple constructs for gene-to-structure projects and have worked on numerous different protein targets and delivered several co-crystal structures. Our services include -
Electron Density Maps
Synchrotron beam services
Ligand binding analysis
Advice on medicinal chemistry design
Crystal hit optimization (additive/detergent screening, sparse matrix grid)
Protein (in the presence of ligand or apo) crystallization screening using commercial kits
Diffraction data collected using in-house x-rays
Fragment Screening Services
We have in-house libraries and resources designed with chemo-genomic tools that allow us to more accurately identify critical fragment leads.
Biophysical Analysis Services
Our biophysical analysis services including -
Measurement of the melting temperature of proteins
Mass spectrometry including intact mass measurement and protein identification
Thermal shift assay processing
Identification and assessment of compounds binding with proteins
Identifying appropriate protein storage buffers
Surface plasmon resonance, including Kon, KD, and Koff in a single injection, screening of low Mw fragments, use of Pioneer FE system, and analysis of irreversible inhibition by Kinact/Kl or Kon Cc.
Recombinant Protein Expression and Purification Services
We are one of the top structural biology services firms and provide high-quality proteins for structural and biophysical studies, high throughput screening, and enzymatic assays. Our services include -
High throughput screening in different expression systems such as mammalian cells, baculo-insect, and E. coli.
Various chromatography stages using highly-efficient AKTA purification systems
Expression optimization and scale-up
Refolding from inclusion bodies
Ion exchange chromatography services
Cell culture within flasks and wave bags
Affinity chromatography services
Size exclusion chromatography services
Purity > 95% (on SDS-PAGE)
Co-expression with chaperons or in the regulatory domain
Protein Production and Crystallization Services
At Outsource2india, our protein production and crystallization services cover purification, cloning, crystallization, and expression of target proteins. We make use of modern and high-quality laboratory equipment to provide all our services. Our services include -
Robotic nanolitre-scale screening and imaging
Optimization of conditions for crystal growth
Co-crystallization of ligands
Screening with known ligands
Stable Cell Lines Generation Services
We handle target genes that cover kinases, ion channels, GPCRs, carboxylases, etc. to generate stables within different cell backgrounds through the use of lentiviral-mediated or plasmid-mediated transfection.
We are a leading structural biology service providing company and our in-house library consists of a high-quality collection of important proteins that can be used for rapid x-ray structure determination.
X-ray Crystallography Services
We perform high-resolution structure determination using X-ray crystallography to support both integrated and stand-alone drug discovery projects.
When you offshore structural biology research services to us, you get access to a team of dedicated and qualified research professionals that use cutting-edge software tools and technologies to deliver outstanding results.
Our ISO/IEC 27001:2013 ISMS-certification demonstrates that we are committed to adhering to the strictest global standards related to data security. Only researchers that have signed strict NDAs will be allowed to access your data.
Single Point of Contact
When you outsource to us, you will not need to spend any time waiting to get your queries resolved. We will assign a project manager that will always be available during your work hours to answer your queries (if any).
Client Success Stories
Flatworld Provides a Patient Dashboard for Pharmaceutical Company
Our team developed a highly efficient and effective patient dashboard for a pharmaceutical company based in Hong Kong.
Outsource Structural Biology Services to Flatworld Solutions
Flatworld Solutions is a pioneer in providing affordable and high-quality structural biology services. We have a team of dedicated, experienced, and qualified professionals that will go the extra mile to provide the best services possible. We also use the latest scientific equipment and tools to provide superior results to our clients.
If you are looking for high-quality and affordable structural biology services, get in touch with us today.